Now that Robert Downey Jr. is officially out of the Marvel universe, the comic book franchise is set to revive the Fantastic Four. While now may be the time to drop in an Arrested Development reference, we have the odds on who may be pulling on the spandex for the dream team in 2022.

Giancarlo Esposito is the early frontrunner at +350 to fill the role of the villain Doctor Doom. Esposito is better known for his role as Gus Frigg in Better Call Saul and Breaking Bad. The Danish-born actor is making waves as the villain of the new Star Wars series The Mandalorian. Cillian Murphy of the Chris Nolan Batman series and BBC’s Peaky Blinders is the second favourite behind Esposito at +500 for the role.

Anthony Ramos is a slight favourite to claim the role of the human torch. Zac Efron also has a claim to the role first filled by Chris Evans in the film version (If you don’t count the 94 Roger Corman take). The husband-and-wife team of Emily Blunt and John Krasinski are the favourites for the roles of the Invisible Woman and Mr Fantastic. The two were last together in A Quiet Place. 

The Thing looms as an interesting choice for the quartet, with the Rock, John Cena and Terry Crews outsiders to fulfil the role. According to Bodog, Stephen Graham at +400 is the favourite to land the role. Graham is better known for his role as Scrum in the Pirates of the Caribbean series.