Liverpool could end Marco Silva’s Everton reign with victory in the Merseyside Derby, while Jose Mourinho takes his Tottenham Hotspur team to Old Trafford to get one over his old employers and Chelsea search for a saviour at Stamford Bridge

Whisper it quietly, but while Manchester City and Chelsea flounder, Leicester City go from strength to strength, with many observers saying that this current squad is better than the one that won the Premier League title in 2015/16. Can The Foxes beat Watford? Yes, easily. Will that be enough to make up any ground on Liverpool as they host their noiseless neighbours? That really is the question.

Elsewhere, Arsenal take on Brighton desperate for points, Southampton and Norwich find out who has a chance of survival at St. Mary’s and Manchester City travelling to a cold Tuesday in Burnley to revive their fortunes, we start our previews in West London.

Chelsea vs. Aston Villa (Wednesday 4th December, 7:30 pm GMT kick-off)