Odds courtesy of OddsShark.com

This promises to a be a most unique NFL season because fans will not be in attendance at most stadiums around the league – at least for a while. If things get better with the coronavirus, that could change. Of course, if things get worse regarding COVID-19, the season might not even finish.

There are some excellent Week 1 matchups on Sunday, but without question one stands apart: Tampa Bay Buccaneers at New Orleans Saints with a 4:25 p.m. ET kickoff. It’s the Bucs and NFC debut of six-time Super Bowl winner Tom Brady – not to mention also the Bucs debuts of Leonard Fournette, LeSean McCoy and Rob Gronkowski.

Meanwhile, this could be the final season opener for Saints quarterback Drew Brees as he’s a possibility to retire with a TV job lined up. Brees ranks No. 1 all-time in NFL passing yards and touchdowns and Brady is second. Needless to say, both are first-ballot unanimous Hall of Famers down the road. Brady’s Bucs are 3.5-point underdogs, which is notable as Brady hadn’t been a regular-season dog with his former New England Patriots team since November 2014. Tampa Bay is 4-17 SU in its past 21 as a road dog, but none of those teams had Brady.