What are the odds that your ticket has the winning numbers for the September 26 Powerball jackpot drawing? Although the odds are slim – 175 million to 1 – that you will be the sole winner of $267 million jackpot on Saturday night, it’s about to get even harder to win the top prize in the popular lottery game. According to USA Today , the odds will increase to 1 in almost 293 million starting on October 7 by adding more numbers to pick from.