Week 5 Thursday Night Football Betting Preview

It is on backup QB Drew Stanton to guide the Arizona Cardinals to a rare road win against the San Francisco 49ers on Thursday night.

Odds courtesy of OddsShark.com

With Carson Palmer (concussion) out of action, the Cardinals are 3.5-point favorites against the 49ers in a matchup of two 1-3 NFC West teams. The total is 42 points. The Cardinals are a -175 favorite on the moneyline, with the 49ers offering +155 for an outright victory.

The Cardinals are 1-6 straight-up and 2-5 against the spread in their last seven road games against the 49ers. While San Francisco was expected to struggle, Arizona is underachieving in spite of skill position talent such as RB David Johnson and the WR trio of John Brown, Larry Fitzgerald and Michael Floyd.