The 2017 Kentucky Derby has four clear-cut favorites atop the betting board led by Classic Empire at +425 (wager $100 to win $425). But an unfavorable post position for Classic Empire at No. 14 gives three other horses – Always Dreaming (+450), McCraken (+600) and Irish War Cry (+600) – a solid shot to win the 143rd Run for the Roses at Churchill Downs in Louisville on Saturday as well.

Odds courtesy of OddsShark.com

Only two horses have ever won the Kentucky Derby from the No. 14 spot, with the last coming way back in 1961 (Carry Back). One favorable trend for Classic Empire though is the fact that the favorite has won the first Triple Crown race each of the last four years.

Classic Empire won the Breeders’ Cup Juvenile last year and will be trying to follow in the footsteps of Nyquist (2016) and Street Sense (2007) as previous winners of both that race and the Kentucky Derby. Classic Empire also won the Arkansas Derby.