Three of the four Sweet 16 matchups on Friday are expected to be close from a betting perspective. The exception is the top-seeded North Carolina Tar Heels (29-7) taking on the fourth-seeded Butler Bulldogs (25-8) as seven-point favorites in the South Region.

Odds courtesy of OddsShark.com

The Tar Heels remain among the favorites to win the national championship on April 3, so it is no surprise to see them listed as the biggest chalk at the FedExForum in Memphis. They have gone 16-4 straight up in their last 20 games versus teams with winning records and 5-1-1 against the spread in their past seven as favorites of seven or more.

The Bulldogs have won the previous two meetings, and they are also 7-1 ATS in their last eight as underdogs, making for a very intriguing game despite the line.